Tuesday, September 26, 2017

Coming Soon, Pig Organ Transplants Into Humans!

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Could A Human Ever Survive With A Pig Heart?
Seeker
Published on Apr 27, 2016
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Xenotransplantation-The Future Of Heart Transplantation? (David Cooper, MD, PhD)
The New Orleans Conference
Published on Aug 17, 2017
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Fields of pigs to be bred in Matrix-like bio-factories, then murdered for organ transplants into humans
by: Mike Adams        
Monday, September 25, 2017
(Natural News) The latest horror story from the world of dangerous medicine and genetic engineering involves the mass breeding of pigs in bio-factories, to be murdered and organ harvested for human transplants. The New York Times, not surprisingly, celebrates this mass murder of conscious beings (pigs) in order to generate massive profits for the organ harvesting and transplant industry.
Missing in all this is any real discussion of:
  • The horrendous medical ethics of growing and sacrificing conscious beings for their organs. Is this not a gross violation of the Hippocratic Oath?
  • The profit incentive of the transplant industry to grow and mass murder animals for transplant profits.
  • The question of whether all organ transplant candidates actually deserve replacement organs if they are living lifestyles that destroyed their own organs (smoking, substance abuse, alcohol addiction, etc.).
Most (but not all) transplant recipients, it turns out, are people who destroyed their own organs through substance abuse in the first place. Are bio-factories full of pigs now going to provide an endless stream of replacement organs for people who keep smoking, abusing alcohol and abusing recreational drugs while destroying their organs? Some other relevant questions in all this:
  • How many pigs must be murdered — and how many millions of dollars of health insurance payments — must be consumed in order to replace the organs of substance abusers who would otherwise not get a second, third or fourth chance?
  • Is their a limit for transplant organs for people who are substance abusers?
  • Should taxpayers have to foot the bill for endless organ transplants for people who choose to live horribly unhealthy lifestyles? And if Republicans say they don’t want to cover unlimited transplants for drug abusers, won’t they be accused of “literally killing people” for denying them health insurance coverage for an endless stream of organ transplants?
  • Will the practice of medicine now involve the mass murder of animals in order to supply a steady stream of transplant organs?
Coming next: Human babies grown in labs and sacrificed for organ harvesting
As I argue in my video below, the organ transplant industry is steeped in medical ethics violations and the mass murder of conscious beings. It won’t be long, I explain, before the industry will want to genetically engineer human babies to be grown for organ harvesting.
After all, the “progressives” in society today have no qualms about murdering babies during “partial birth abortions” in the name of “medical science,” right? So they won’t think anything of raising massive bio-factories / farms of human babies with genetically engineered tissue to be murdered and harvested for their organs. Planned Parenthood is doing much the same thing right now, and they’re doing it with taxpayer dollars while calling it “medical science.
Is there any amount of murder, suffering and death that won’t be called “medical science” by the wildly unethical medical status quo?
Watch my video to learn more:

Pigs to be bred and MURDERED for organ transplants into humans
Published on Sep 25, 2017
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Pig organs to be used for human transplants in just TWO years
Animal organs could be transplanted into people within years, scientists have claimed.
By Nicole Stinson
Published: Fri, Aug 11, 2017
George Church, professor of genetics at Harvard Medical School, revealed that genetically modified pig organs could be used in transplants to human – as the NHS battles to find suitable donors.
Professor Church initially studied the initial hazards of using pigs’ DNA, including viral infections and rejection by the human body, but found the former could be solved with genetic modification.
He said: “The viruses are particularly troubling.
“Swine flu and ebola and HIV were all cases where the virus of the animal was in close contact with a human.
“Nothing could be closer contact than an organ in the middle of the body.”
Professor Church and his colleagues created genetically modified pigs with viruses unactivated in their DNA.
The new DNA was then put into an embryo and implanted into a surrogate sow.
According to the scientists, the piglets were born healthy and completely free of retroviruses.
Scientists modified pigs' DNA before putting it in an embryo
Professor Church and his team are now hopeful that the technology may soon be trialled in people.
He added: “The very earliest clinical trials could be in two years.”
The news comes as more than 6,000 patients waiting for an organ transplant in the UK, according to Government figures.
Sally Johnson, NHS Blood and Transplant Director of Organ Donation and Transplantation said: “We’re encouraged that the number of people becoming donors has helped reduce how long desperately ill people wait before they receive a kidney transplant.
“However there is a still a severe shortage of donated organs. Two and a half years is far too long to wait for a kidney and far too many people die without ever receiving the transplant they need. “
But other scientists have cautiously applauded the study’s technical advances.
Bruce Whitelaw, from the University of Edinburgh, told the Times: “This tells us we can use these wonderful tools to chop up the genome at multiple sites and it goes back together in the right way.”
However he added “the main challenge is still to overcome the overall immune response”.
Meanwhile Ian McConnell, from the University of Cambridge, said: “The use of human organs for transplantation only meets a small percentage of the total and growing number of individuals in desperate need of organ transplantation.
“But the use of animal organs such is not without serious ethical concerns.”

In 2014 Margaret Mann, a retired carer from West Sussex, became the first patient in the world to have a heart valve made of pig tissue.
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Gene Editing Spurs Hope for Transplanting Pig Organs Into Humans
By Gina Kolata
August 10, 2017
In a striking advance that helps open the door to organ transplants from animals,researchers have created gene-edited piglets cleansed of viruses that might causedisease in humans.
The experiments, reported on Thursday in the journal Science, may make it possible one day to transplant livers, hearts and other organs from pigs into humans, a hope that experts had all but given up.
If pig organs were shown to be safe and effective, “they could be a real game changer,” said Dr. David Klassen, chief medical officer at the United Network for Organ Sharing, a private, nonprofit organization that manages the nation’s transplant system.
There were 33,600 organ transplants last year, and 116,800 patients on waiting lists, according to Dr. Klassen, who was not involved in the new study. “There’s a big gap between organ supply and organ demand,” he said.
Dr. George Church, a geneticist at Harvard who led the experiments, said the first pig-to-human transplants could occur within two years.
The new research combines two great achievements in recent years — gene editing and cloning — and is unfolding quickly. But the work is novel and its course
unpredictable, Dr. Klassen noted.
It may be years before enough is known about the safety of pig organ transplants to allow them to be used widely.
The idea of using pigs as organ factories has tantalized investigators for decades.
Porcine organs can be the right size for human transplantation, and in theory, similar enough to function in patients.
But the prospect also raises thorny questions about animal exploitation and welfare. Already an estimated 100 million pigs are killed in the United States each year for food.
Scientists pursuing this goal argue that the few thousand pigs grown for their organs would represent just a small fraction of that total, and that they would be used to save human lives. The animals would be anesthetized and killed humanely.
Major religious groups have already weighed in, generally concluding that pig organs are acceptable for lifesaving transplants, noted Dr. Jay Fishman, co-director of the transplant program at Massachusetts General Hospital. Pig heart valves already are routinely transplanted into patients.
(A survey in the 1990s by Dr. Fishman and his colleagues found that some leaders in the Jewish and Muslim communities did not endorse pig kidneys for
transplant, , reasoning that patients with kidney failure can survive with dialysis.)
Scientists began pursuing the idea of pig organs for transplant in the 1990s. But in 1998, Dr. Fishman and his colleagues discovered that hidden in pig DNA were genes for viruses that resembled those causing leukemia in monkeys.
When researchers grew pig cells next to human embryonic kidney cells in the laboratory, these viruses — known as retroviruses — spread to the human cells. Once infected, the human cells were able to infect other human cells.
Fears that pig organs would infect humans with bizarre retroviruses brought the research to a halt. But it was never clear how great this threat really was, and as years have gone by, many experts, including Dr. Fishman, have become less
concerned.
Some patients with diabetes have received pig pancreas cells, hidden in a sort of sheath so the immune system will not reject them. And burn patients sometimes get grafts made of pig skin. The pig skin is eventually rejected by the body, but it was
never meant to be permanent anyway.
There is no evidence that any of these patients were infected with porcine retroviruses. In any event, said Dr. A. Joseph Tector, a transplant surgeon at the
University of Alabama at Birmingham, pig retroviruses are very sensitive to the drugs used to treat H.I.V.
“We don’t know that if we transplant pig organs with the viruses that they will transmit infections, and we don’t know that the infections are dangerous,” Dr.
Fishman said. “I think the risk to society is very low.”
Dr. Church and his colleagues thought the retrovirus question could be resolved with Crispr, the new gene-editing technology. They took cells from pigs and snipped the viral DNA from their genomes. Then the scientists cloned the edited cells.
Each pig cell was brought back to its earliest developmental stage and thenslipped into an egg, giving it the genetic material to allow the egg to develop into an embryo. The embryos were implanted in sows and grew into piglets that were
genetically identical to the pig that supplied the initial cell.
Cloning often fails; most of the embryos and fetuses died before birth, and some piglets died soon after they were born. But Dr. Church and his colleagues ended up with 15 living piglets, the oldest now 4 months old. None have the retroviruses.
Dr. Church founded a company, eGenesis, in hopes of selling the genetically altered pig organs. Eventually, Dr. Church says, the company wants to engineer pigs
with organs so compatible with humans that patients will not need to take antirejection drugs.
Dr. David Sachs, a professor of surgery at Columbia University, was skeptical that it would be straightforward to make pigs with such compatible organs.
“I am afraid that he may find these goals more difficult to achieve than he expects, but I would be happy to be mistaken,” said Dr. Sachs, who is also studying ways to create pigs suitable for organ donation.
Part of the organ rejection problem is already being solved with gene editingand cloning. It is an issue that emerged in the early 1980s when surgeons put a pig heart into a baboon. To their shock, the baboon died in minutes.
Researchers soon discovered that pig organs are covered with carbohydrate molecules that mark the organs for immediate destruction by human antibodies.
Dr. David Cooper, at the University of Alabama at Birmingham, and his colleagues, including Dr. Tector, have used gene editing and cloning to make pigs
without the carbohydrates on the surfaces of their organs.
They successfully transplanted hearts and kidneys from those pigs into monkeys and baboons. So far, the animals have lived more than a year with no problems, Dr.Tector said.
They also gave insulin-producing islet cells from a pig to diabetic monkeys, and the monkeys lived for a year without requiring insulin. In partnership with United Therapeutics, the group has already built a farm for gene-edited pigs.
Dr. Church says he, too, is making pigs whose organs lack the carbohydrates, and he wants to combine the two advances so the organs also do not have
retroviruses. The Alabama group, though, does not think pig retroviruses are a major concern.
Surgeons are used to evaluating the risks of infection from transplanted organs, Dr. Tector said. The advantage of the transplant to the desperately ill recipient often outweighs that risk.
To some, the idea of growing pigs to create organs is distasteful. Many patients may prefer a human organ, Dr. Cooper acknowledged, but that is not always
possible.
“About 22 people a day die waiting for a transplant,” he said. “If you could help them with a pig organ, wouldn’t that be wonderful?”
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The Future of Animal-to-Human Organ Transplants
Could a genetically engineered pig heart one day function in a person?
By Heather Hansman
smithsonian.com
September 17, 2015
This pig could be growing a heart or lungs for a transplant. (Lars Schlageter)
On a farm in Virginia, a company called Revivicor is breeding pigs that have some genetic similarities to humans. The scientists call them GalSafe pigs, and they have added five human genes to the pigs' livers, kidneys and hearts. The hope is that the organs can be harvested and used for transplants, and that human bodies won’t reject them.
It sounds like science fiction, but it’s sort of working. Revivicor (started by the British company PPL Therapeutics that produced Dolly the cloned sheep) is making strides in the slowly growing field of xenotransplantation, or the transplanting of non-human organs or cells into a human body. The first step has been to make transplants from one animal species to another a reality.
Last month, surgeons at the National Heart, Lung, and Blood Institute, in Bethesda, Maryland, managed to keep one of Revivicor's genetically modified pig hearts alive inside a baboon's stomach for 945 days. They were testing the baboon's immune response to the foreign organ, not the pig heart's ability to function as the animal's heart. Humans share more than 90 percent of their DNA with baboons, so transplanting a pig organ into the primate is a step in the right direction.
There’s a shortage of human organs for transplants—an average of 21 people die each day in the United States because they don’t get transplants in time. Lungs or hearts can only stay functional on ice for a few hours, and so they often aren’t used before they expire. Revivicor thinks pig organs can fill that void, and create a much more accessible and plentiful supply of transplantable organs, if only scientists can get our bodies to accept them.
Pigs are genetically distant from humans, but their organs are of a similar size and they’re easy to breed, which is why they’ve been a target for xenotransplantation. Pig valves are already used successfully in heart transplants.
Human-to-human organ transplantation has only been around since the 1950s, and scientists have been working on animal-to-human transplants for almost that long. In the '60s, Keith Reemtsma experimented with transplanting chimpanzee kidneys into humans. Most of them failed within a few weeks, but one woman lived for nine months. Most other attempted xenotransplantations, especially hearts and lungs, have had similar degrees of success. In 1984, in one of the most famous cross-species transplantations, Leonard Bailey transplanted a baboon heart into a infant, Baby Fae. The heart failed after 20 days, but it became a gateway for the first pediatric human-to-human heart transplant a year later. Recently, with genetic engineering, scientists have kept, in addition to the pig heart, a pig kidney alive and functioning in a baboon for 136 days.
So far, cross-species transplantations have been impossible to sustain indefinitely, because the human immune system is built to reject foreign organs. In lab trials, troubles occur when human blood pumps through pig organs. According to Revivicor, the immune response is triggered by natural antibodies directed against the galactose epitope, or the part of the pig cells that determines whether antibodies can attach themselves or not. So the company is working to modify that epitope by adding human thrombomodulin, the protein that coats those epitopes, to the pig’s genome. That makes them seem more human, and, therefore, it is less likely for the body to reject them.
The challenge is to target the genes that human bodies reject and then find ways to edit them. The baboon that survived with the heart transplant was on a heavy course of immunosuppressant drugs and died when it was taken off the regimen. But scientists are still hopeful about the next experiment—actually replacing a baboon's heart with a pig heart.
"Based on the data from long-term surviving grafts, we are hopeful that we will be able to repeat our results in the life-supporting model. This has potential for paving the way for the use of animal organs for transplantation into humans," Muhammad M. Mohiuddin, of the National Heart, Lung, and Blood Institute, told the American Association for Thoracic Surgery.
Part of Revivicor's push for pig organs is personal. Martine Rothblatt, founder of Revivicor's current parent company United Therapeutics, has a daughter with pulmonary arterial hypertension, a lung condition that is usually fatal. The only way to treat it is with a transplant, so she’s sunk time and money into organ transplants and tissue engineering. Revivicor is focusing on hearts and livers before lungs, because lungs are more influenced by the immune system. They've said they want to do the first complete pig-to-human organ transplant within a decade.
Rothblatt's dream for Revivicor to become an assembly line for new organs, so that there’s never a shortage, is just that, a dream. Although there’s been significant progress in how the organs maintain their integrity, direct pig-to-human transplants are still a long ways off.
"The immunological and pathophysiological problems associated with pig xenotransplantation...are significant and probably reflect the fact that it has been 80 million years since the pig and human diverged on the evolutionary scale," wrote David K.C. Cooper, a surgeon at the Thomas E. Starzl Transplantation Institute at the University of Pittsburgh Medical Center,  in a 2012 paper about xenotransplantation. "Therefore, in the words of [German scientist] Claus Hammer, what we are trying to do is to 'outwit evolution.'"
In addition to bodies rejecting the organs, there’s fear about cross-species infection, like swine flu, because humans don't have immunity to viruses that originate in animals. These infections would be especially dangerous, because patients would have to be on immunosuppressants to prevent organ rejection. There’s also tricky moral ground to cross. Bailey's heart transplant is still controversial, and there's worry about both informed consent from the patient's side and animal welfare. Animal rights groups, as you might expect, are opposed to raising animals for the purpose of harvesting their organs.
Anyone doing xenotransplantation in the U.S. has to get clearance from the Food and Drug Administration. The FDA's guidelines on the risks of animal-to-human disease transmission, informed consent and animal welfare are perpetually updated, and they are due for a revision in March 2016.
According to MIT Technology Review, “The last time a doctor transplanted a pig heart into a person, in India in 1996, he was arrested for murder.”
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